The correct answer is D!

None of these will reduce his mortality risk

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A 60-year-old man with recent onset mild exertional chest pain (CCS 1) is found to have single-vessel disease involving his RCA and normal systolic function on a coronary CTA. 

Q: Which of the following antianginal therapies is likely to provide the greatest survival benefit?

A) Carvedilol

B) Amlodipine

C) Isosorbide mononitrate

D) None of these will reduce his mortality risk (Correct)

Rationale

Beta-blockers (BBs), calcium channel blockers (CCBs), and long-acting nitrates each represent effective antianginal therapies. In patients without a history of MI and/or reduced LV systolic function, however, they have not been shown to improve survival. (Knuuti et al. 2020)

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