THE RECOVERY TRIAL News emerged from the UK on June 16 around very promising results with dexamethasone in the treatment of COVID-19 infected patients in the Randomised Evaluation of COVID-19 Therapy (RECOVERY) trial. RECOVERY is a randomized trial investigating whether treatment with either (1)Lopinavir-Ritonavir, (2)Hydroxychloroquine, (3)Corticosteroids, (4)Azithromycin,(5) Convalescent plasma or (6)Tocilizumab prevents death in patients with COVID-19.
Is There a Common Thread Connecting the “Atypical” Presentations of COVID-19? As we hear more about atypical presentations of what was initially viewed as a respiratory infection, it raises the question: is there a common thread related to the pathophysiology of COVID-19 that underlies its presentation in stroke, cardiovascular manifestations, renal failure, coagulopathies, and a
What defines a misdiagnosis, or a “diagnostic error” in medicine? In 2015, the National Academies of Sciences, Engineering, and Medicine’s “Improving Diagnosis in Health Care” defined a diagnostic error as “the failure to establish an accurate and timely explanation of the patient’s health problem(s) or (b) communicate that explanation to the patient.” This comprehensive report
Early in the course of the COVID-19 pandemic, one of the only pieces of “good news” reported by medical literature and the lay press was that children, for the most part, did not appear to be as vulnerable to COVID-19 infection as adults. It was initially thought that perhaps children, when infected, developed milder cases
To date, several pharmaceutical agents have been evaluated in the treatment of COVID-19. On May 23, the first report of a positive response to a therapeutic agent, remdesivir, was reported in the New England Journal of Medicine. The positive topline results of this trial were shared via a press release a few weeks ago. To
Students and teachers across all levels of schooling – elementary through high school to post-secondary education and professional education have changed in light of the COVID-19 pandemic. The physical classroom model has disappeared and may not return in its prior format. To thrive in a remote education world, students and teachers must adapt their learning
Although we will not be placing COVID-19 in our rearview mirror in the foreseeable future, it is already apparent that there will almost certainly be legacies that are actually more positive than negative for the healthcare system at large.
What we are learning about management of COVID-19 infected patients is growing daily. Many clinicians have expressed never having seen anything quite like this; obviously the sheer number of critically ill patients is unprecedented, as is the unique pathophysiology of what occurs in the lungs of COVID patients. The lack of definitive therapies for the
Preparing for and responding to the surge of COVID-19 patients has required healthcare systems to develop and implement new strategies to deal with shortages. Resources that have been in scarce supply include personal protective equipment, ventilators, ICU beds, medications, and IV fluids. Sadly, the resource that is most challenging to recruit in adequate numbers is
From the use of anti-inflammatory and antiviral medications to the use of a “smart ring” to monitor body temperature, the crisis resulting from the COVID-19 pandemic has provided the impetus for clinical and technological innovation. Clinical studies are being quickly initiated at health systems and research organizations around the world to explore a variety of
Today, Monday, April 6, marks the first day of National Public Health Week. If you missed our recent public health-related blogs on the roles of the various public health agencies or our interview with family and public health physician Dr. Angela DeJulius, you can check them out on our website. Each day of National Public
First of all, an enormous thank you to all healthcare workers- especially those on the frontlines-for your selfless dedication during this unprecedented crisis. K2P is working to help keep our clinical audience informed of topics of interest at this time. If you missed our interview with Angela DeJulius, MD regarding the collaboration between public health